Photosensitive and Conductive Hydrogel Induced Innerved Bone Regeneration for Infected Bone Defect Repair (Adv. Healthcare Mater. 3/2023)

Innervation is the initiating factor for bone regeneration and plays a key regulatory role in subsequent vascularization, ossification, mineralization processes. A biomaterial that can induce skeletal-associated neural network reconstruction with high antibacterial activity proposed treatment of infected defects. In article 2201349, Tingfang Sun, Zhiqiang Luo, Xiaodong Guo, co-workers load magnesium-modified black phosphorus nanosheets ([email protected]) GelMA The photosensitive hydrogel has strong improves local microenvironment. [email protected] promotes secretion Schwann cells outgrowth CGRP+ sensory nerve fibers, thus enhancing nerve–bone crosstalk finally realizing innerved regeneration.